Does METHOTREXATE Cause Wernicke's encephalopathy? 43 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 43 reports of Wernicke's encephalopathy have been filed in association with METHOTREXATE (Methotrexate). This represents 0.0% of all adverse event reports for METHOTREXATE.
43
Reports of Wernicke's encephalopathy with METHOTREXATE
0.0%
of all METHOTREXATE reports
7
Deaths
19
Hospitalizations
How Dangerous Is Wernicke's encephalopathy From METHOTREXATE?
Of the 43 reports, 7 (16.3%) resulted in death, 19 (44.2%) required hospitalization, and 5 (11.6%) were considered life-threatening.
Is Wernicke's encephalopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 43 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Wernicke's encephalopathy?
FUROSEMIDE (53)
CYCLOPHOSPHAMIDE (38)
TACROLIMUS (37)
VINCRISTINE (36)
FLUOROURACIL (28)
CYTARABINE (27)
OMEPRAZOLE (27)
METFORMIN (24)
METRONIDAZOLE (21)
ETOPOSIDE (18)
Which METHOTREXATE Alternatives Have Lower Wernicke's encephalopathy Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA