Does MITOTANE Cause Hepatotoxicity? 6 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 6 reports of Hepatotoxicity have been filed in association with MITOTANE (Lysodren). This represents 0.6% of all adverse event reports for MITOTANE.
6
Reports of Hepatotoxicity with MITOTANE
0.6%
of all MITOTANE reports
1
Deaths
0
Hospitalizations
How Dangerous Is Hepatotoxicity From MITOTANE?
Of the 6 reports, 1 (16.7%) resulted in death.
Is Hepatotoxicity Listed in the Official Label?
Yes, Hepatotoxicity is listed as a known adverse reaction in the official FDA drug label for MITOTANE.
What Other Side Effects Does MITOTANE Cause?
Nausea (210)
Fatigue (205)
Off label use (154)
Diarrhoea (123)
Vomiting (97)
Drug ineffective (86)
Decreased appetite (77)
Adrenal insufficiency (76)
Dizziness (76)
Asthenia (70)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which MITOTANE Alternatives Have Lower Hepatotoxicity Risk?
MITOTANE vs MITOXANTRONE
MITOTANE vs MITRAGYNINE\HERBALS
MITOTANE vs MIZORIBINE
MITOTANE vs MOBOCERTINIB
MITOTANE vs MOCLOBEMIDE