Does NIVOLUMAB Cause Hepatotoxicity? 324 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 324 reports of Hepatotoxicity have been filed in association with NIVOLUMAB (OPDIVO). This represents 0.4% of all adverse event reports for NIVOLUMAB.
324
Reports of Hepatotoxicity with NIVOLUMAB
0.4%
of all NIVOLUMAB reports
46
Deaths
130
Hospitalizations
How Dangerous Is Hepatotoxicity From NIVOLUMAB?
Of the 324 reports, 46 (14.2%) resulted in death, 130 (40.1%) required hospitalization, and 22 (6.8%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
Yes, Hepatotoxicity is listed as a known adverse reaction in the official FDA drug label for NIVOLUMAB.
What Other Side Effects Does NIVOLUMAB Cause?
Death (11,216)
Malignant neoplasm progression (9,363)
Off label use (5,208)
Diarrhoea (4,692)
Fatigue (3,709)
Pyrexia (3,454)
Intentional product use issue (3,297)
Rash (2,816)
Nausea (2,805)
Decreased appetite (2,619)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which NIVOLUMAB Alternatives Have Lower Hepatotoxicity Risk?
NIVOLUMAB vs NIVOLUMAB\RELATLIMAB-RMBW
NIVOLUMAB vs NIZATIDINE
NIVOLUMAB vs NOMEGESTROL
NIVOLUMAB vs NORDAZEPAM
NIVOLUMAB vs NOREPINEPHRINE