Does OSIMERTINIB Cause Hepatotoxicity? 87 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 87 reports of Hepatotoxicity have been filed in association with OSIMERTINIB (TAGRISSO). This represents 0.3% of all adverse event reports for OSIMERTINIB.
87
Reports of Hepatotoxicity with OSIMERTINIB
0.3%
of all OSIMERTINIB reports
6
Deaths
13
Hospitalizations
How Dangerous Is Hepatotoxicity From OSIMERTINIB?
Of the 87 reports, 6 (6.9%) resulted in death, 13 (14.9%) required hospitalization, and 4 (4.6%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for OSIMERTINIB. However, 87 reports have been filed with the FAERS database.
What Other Side Effects Does OSIMERTINIB Cause?
Death (10,423)
Malignant neoplasm progression (2,920)
Diarrhoea (1,408)
Drug resistance (1,026)
Fatigue (819)
Rash (772)
Decreased appetite (706)
Drug ineffective (627)
Dyspnoea (621)
Nausea (610)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which OSIMERTINIB Alternatives Have Lower Hepatotoxicity Risk?
OSIMERTINIB vs OSPEMIFENE
OSIMERTINIB vs OSPHENA
OSIMERTINIB vs OVINE DIGOXIN IMMUNE FAB
OSIMERTINIB vs OXACILLIN
OSIMERTINIB vs OXALIPLATIN