Does PACLITAXEL Cause Hepatotoxicity? 356 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 356 reports of Hepatotoxicity have been filed in association with PACLITAXEL (PACLITAXEL PACLITAXEL). This represents 0.5% of all adverse event reports for PACLITAXEL.
356
Reports of Hepatotoxicity with PACLITAXEL
0.5%
of all PACLITAXEL reports
51
Deaths
101
Hospitalizations
How Dangerous Is Hepatotoxicity From PACLITAXEL?
Of the 356 reports, 51 (14.3%) resulted in death, 101 (28.4%) required hospitalization, and 21 (5.9%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PACLITAXEL. However, 356 reports have been filed with the FAERS database.
What Other Side Effects Does PACLITAXEL Cause?
Neutropenia (4,553)
Nausea (4,521)
Dyspnoea (4,519)
Diarrhoea (4,289)
Off label use (4,075)
Anaemia (3,949)
Neuropathy peripheral (3,508)
Malignant neoplasm progression (3,484)
Fatigue (3,418)
Death (3,143)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which PACLITAXEL Alternatives Have Lower Hepatotoxicity Risk?
PACLITAXEL vs PACRITINIB
PACLITAXEL vs PALBOCICLIB
PACLITAXEL vs PALIPERIDONE
PACLITAXEL vs PALIVIZUMAB
PACLITAXEL vs PALONOSETRON