Does PALBOCICLIB Cause Hepatotoxicity? 179 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 179 reports of Hepatotoxicity have been filed in association with PALBOCICLIB (Ibrance). This represents 0.2% of all adverse event reports for PALBOCICLIB.
179
Reports of Hepatotoxicity with PALBOCICLIB
0.2%
of all PALBOCICLIB reports
9
Deaths
26
Hospitalizations
How Dangerous Is Hepatotoxicity From PALBOCICLIB?
Of the 179 reports, 9 (5.0%) resulted in death, 26 (14.5%) required hospitalization, and 5 (2.8%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PALBOCICLIB. However, 179 reports have been filed with the FAERS database.
What Other Side Effects Does PALBOCICLIB Cause?
Fatigue (15,190)
White blood cell count decreased (11,273)
Neoplasm progression (10,885)
Death (8,410)
Nausea (8,189)
Neutropenia (6,423)
Alopecia (6,201)
Diarrhoea (5,635)
Asthenia (3,660)
Off label use (3,405)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which PALBOCICLIB Alternatives Have Lower Hepatotoxicity Risk?
PALBOCICLIB vs PALIPERIDONE
PALBOCICLIB vs PALIVIZUMAB
PALBOCICLIB vs PALONOSETRON
PALBOCICLIB vs PAMIDRONATE
PALBOCICLIB vs PAMIDRONIC ACID