Does PAZOPANIB Cause Hepatotoxicity? 152 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 152 reports of Hepatotoxicity have been filed in association with PAZOPANIB (Pazopanib). This represents 0.7% of all adverse event reports for PAZOPANIB.
152
Reports of Hepatotoxicity with PAZOPANIB
0.7%
of all PAZOPANIB reports
28
Deaths
30
Hospitalizations
How Dangerous Is Hepatotoxicity From PAZOPANIB?
Of the 152 reports, 28 (18.4%) resulted in death, 30 (19.7%) required hospitalization, and 5 (3.3%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PAZOPANIB. However, 152 reports have been filed with the FAERS database.
What Other Side Effects Does PAZOPANIB Cause?
Death (3,767)
Diarrhoea (2,907)
Fatigue (1,883)
Nausea (1,879)
Malignant neoplasm progression (1,471)
Drug ineffective (1,135)
Decreased appetite (1,116)
Vomiting (1,072)
Hypertension (1,004)
Malaise (764)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which PAZOPANIB Alternatives Have Lower Hepatotoxicity Risk?
PAZOPANIB vs PEANUT
PAZOPANIB vs PEG INTERFERON
PAZOPANIB vs PEG-INTERFERON ALFA 2A
PAZOPANIB vs PEGASPARGASE
PAZOPANIB vs PEGASYS