Does PEGASPARGASE Cause Bone marrow failure? 130 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 130 reports of Bone marrow failure have been filed in association with PEGASPARGASE (ONCASPAR). This represents 1.1% of all adverse event reports for PEGASPARGASE.
130
Reports of Bone marrow failure with PEGASPARGASE
1.1%
of all PEGASPARGASE reports
34
Deaths
89
Hospitalizations
How Dangerous Is Bone marrow failure From PEGASPARGASE?
Of the 130 reports, 34 (26.2%) resulted in death, 89 (68.5%) required hospitalization, and 40 (30.8%) were considered life-threatening.
Is Bone marrow failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEGASPARGASE. However, 130 reports have been filed with the FAERS database.
What Other Side Effects Does PEGASPARGASE Cause?
Febrile neutropenia (1,589)
Pyrexia (706)
Febrile bone marrow aplasia (668)
Sepsis (548)
Vomiting (530)
Neutropenia (521)
Abdominal pain (469)
Hypertriglyceridaemia (399)
Hypotension (388)
Thrombocytopenia (382)
What Other Drugs Cause Bone marrow failure?
CYCLOPHOSPHAMIDE (1,834)
METHOTREXATE (1,401)
ETOPOSIDE (1,081)
RITUXIMAB (1,060)
CYTARABINE (1,052)
VINCRISTINE (1,001)
DOXORUBICIN (1,000)
PALBOCICLIB (951)
CARBOPLATIN (855)
BEVACIZUMAB (835)
Which PEGASPARGASE Alternatives Have Lower Bone marrow failure Risk?
PEGASPARGASE vs PEGASYS
PEGASPARGASE vs PEGCETACOPLAN
PEGASPARGASE vs PEGFILGRASTIM
PEGASPARGASE vs PEGFILGRASTIM-APGF
PEGASPARGASE vs PEGFILGRASTIM-BMEZ