Does PEGASPARGASE Cause Clostridium difficile colitis? 262 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 262 reports of Clostridium difficile colitis have been filed in association with PEGASPARGASE (ONCASPAR). This represents 2.3% of all adverse event reports for PEGASPARGASE.
262
Reports of Clostridium difficile colitis with PEGASPARGASE
2.3%
of all PEGASPARGASE reports
213
Deaths
50
Hospitalizations
How Dangerous Is Clostridium difficile colitis From PEGASPARGASE?
Of the 262 reports, 213 (81.3%) resulted in death, 50 (19.1%) required hospitalization, and 7 (2.7%) were considered life-threatening.
Is Clostridium difficile colitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEGASPARGASE. However, 262 reports have been filed with the FAERS database.
What Other Side Effects Does PEGASPARGASE Cause?
Febrile neutropenia (1,589)
Pyrexia (706)
Febrile bone marrow aplasia (668)
Sepsis (548)
Vomiting (530)
Neutropenia (521)
Abdominal pain (469)
Hypertriglyceridaemia (399)
Hypotension (388)
Thrombocytopenia (382)
What Other Drugs Cause Clostridium difficile colitis?
CYCLOPHOSPHAMIDE (717)
PREDNISONE (619)
DEXAMETHASONE (575)
METHOTREXATE (562)
ETOPOSIDE (503)
CYTARABINE (489)
VINCRISTINE (482)
LENALIDOMIDE (388)
METHYLPREDNISOLONE (385)
CIPROFLOXACIN (378)
Which PEGASPARGASE Alternatives Have Lower Clostridium difficile colitis Risk?
PEGASPARGASE vs PEGASYS
PEGASPARGASE vs PEGCETACOPLAN
PEGASPARGASE vs PEGFILGRASTIM
PEGASPARGASE vs PEGFILGRASTIM-APGF
PEGASPARGASE vs PEGFILGRASTIM-BMEZ