Does PEGASPARGASE Cause Constipation? 97 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 97 reports of Constipation have been filed in association with PEGASPARGASE (ONCASPAR). This represents 0.8% of all adverse event reports for PEGASPARGASE.
97
Reports of Constipation with PEGASPARGASE
0.8%
of all PEGASPARGASE reports
12
Deaths
80
Hospitalizations
How Dangerous Is Constipation From PEGASPARGASE?
Of the 97 reports, 12 (12.4%) resulted in death, 80 (82.5%) required hospitalization, and 14 (14.4%) were considered life-threatening.
Is Constipation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEGASPARGASE. However, 97 reports have been filed with the FAERS database.
What Other Side Effects Does PEGASPARGASE Cause?
Febrile neutropenia (1,589)
Pyrexia (706)
Febrile bone marrow aplasia (668)
Sepsis (548)
Vomiting (530)
Neutropenia (521)
Abdominal pain (469)
Hypertriglyceridaemia (399)
Hypotension (388)
Thrombocytopenia (382)
What Other Drugs Cause Constipation?
LENALIDOMIDE (9,635)
NIRAPARIB (4,128)
ADALIMUMAB (4,063)
SEMAGLUTIDE (4,036)
TIRZEPATIDE (3,417)
ERENUMAB-AOOE (3,104)
MORPHINE (2,979)
OXYCODONE (2,747)
PALBOCICLIB (2,705)
POMALIDOMIDE (2,374)
Which PEGASPARGASE Alternatives Have Lower Constipation Risk?
PEGASPARGASE vs PEGASYS
PEGASPARGASE vs PEGCETACOPLAN
PEGASPARGASE vs PEGFILGRASTIM
PEGASPARGASE vs PEGFILGRASTIM-APGF
PEGASPARGASE vs PEGFILGRASTIM-BMEZ