Does PEGASPARGASE Cause Hepatic encephalopathy? 21 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 21 reports of Hepatic encephalopathy have been filed in association with PEGASPARGASE (ONCASPAR). This represents 0.2% of all adverse event reports for PEGASPARGASE.
21
Reports of Hepatic encephalopathy with PEGASPARGASE
0.2%
of all PEGASPARGASE reports
13
Deaths
18
Hospitalizations
How Dangerous Is Hepatic encephalopathy From PEGASPARGASE?
Of the 21 reports, 13 (61.9%) resulted in death, 18 (85.7%) required hospitalization, and 7 (33.3%) were considered life-threatening.
Is Hepatic encephalopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEGASPARGASE. However, 21 reports have been filed with the FAERS database.
What Other Side Effects Does PEGASPARGASE Cause?
Febrile neutropenia (1,589)
Pyrexia (706)
Febrile bone marrow aplasia (668)
Sepsis (548)
Vomiting (530)
Neutropenia (521)
Abdominal pain (469)
Hypertriglyceridaemia (399)
Hypotension (388)
Thrombocytopenia (382)
What Other Drugs Cause Hepatic encephalopathy?
ACETAMINOPHEN (562)
RIBAVIRIN (512)
LENVATINIB (502)
RIFAXIMIN (462)
SOFOSBUVIR (360)
BEVACIZUMAB (210)
LEDIPASVIR\SOFOSBUVIR (180)
ATEZOLIZUMAB (178)
SORAFENIB (169)
DACLATASVIR (165)
Which PEGASPARGASE Alternatives Have Lower Hepatic encephalopathy Risk?
PEGASPARGASE vs PEGASYS
PEGASPARGASE vs PEGCETACOPLAN
PEGASPARGASE vs PEGFILGRASTIM
PEGASPARGASE vs PEGFILGRASTIM-APGF
PEGASPARGASE vs PEGFILGRASTIM-BMEZ