Does PEGASPARGASE Cause Hepatocellular injury? 173 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 173 reports of Hepatocellular injury have been filed in association with PEGASPARGASE (ONCASPAR). This represents 1.5% of all adverse event reports for PEGASPARGASE.
173
Reports of Hepatocellular injury with PEGASPARGASE
1.5%
of all PEGASPARGASE reports
2
Deaths
48
Hospitalizations
How Dangerous Is Hepatocellular injury From PEGASPARGASE?
Of the 173 reports, 2 (1.2%) resulted in death, 48 (27.7%) required hospitalization, and 1 (0.6%) were considered life-threatening.
Is Hepatocellular injury Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEGASPARGASE. However, 173 reports have been filed with the FAERS database.
What Other Side Effects Does PEGASPARGASE Cause?
Febrile neutropenia (1,589)
Pyrexia (706)
Febrile bone marrow aplasia (668)
Sepsis (548)
Vomiting (530)
Neutropenia (521)
Abdominal pain (469)
Hypertriglyceridaemia (399)
Hypotension (388)
Thrombocytopenia (382)
What Other Drugs Cause Hepatocellular injury?
ACETAMINOPHEN (1,761)
METHOTREXATE (683)
ATORVASTATIN (610)
SULFAMETHOXAZOLE\TRIMETHOPRIM (415)
ENOXAPARIN (365)
TRAMADOL (349)
AMOXICILLIN (347)
ESOMEPRAZOLE (341)
PANTOPRAZOLE (340)
VINCRISTINE (306)
Which PEGASPARGASE Alternatives Have Lower Hepatocellular injury Risk?
PEGASPARGASE vs PEGASYS
PEGASPARGASE vs PEGCETACOPLAN
PEGASPARGASE vs PEGFILGRASTIM
PEGASPARGASE vs PEGFILGRASTIM-APGF
PEGASPARGASE vs PEGFILGRASTIM-BMEZ