Does PEGASPARGASE Cause Venoocclusive liver disease? 122 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 122 reports of Venoocclusive liver disease have been filed in association with PEGASPARGASE (ONCASPAR). This represents 1.1% of all adverse event reports for PEGASPARGASE.
122
Reports of Venoocclusive liver disease with PEGASPARGASE
1.1%
of all PEGASPARGASE reports
17
Deaths
74
Hospitalizations
How Dangerous Is Venoocclusive liver disease From PEGASPARGASE?
Of the 122 reports, 17 (13.9%) resulted in death, 74 (60.7%) required hospitalization, and 14 (11.5%) were considered life-threatening.
Is Venoocclusive liver disease Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEGASPARGASE. However, 122 reports have been filed with the FAERS database.
What Other Side Effects Does PEGASPARGASE Cause?
Febrile neutropenia (1,589)
Pyrexia (706)
Febrile bone marrow aplasia (668)
Sepsis (548)
Vomiting (530)
Neutropenia (521)
Abdominal pain (469)
Hypertriglyceridaemia (399)
Hypotension (388)
Thrombocytopenia (382)
What Other Drugs Cause Venoocclusive liver disease?
CYCLOPHOSPHAMIDE (911)
BUSULFAN (765)
FLUDARABINE (649)
VINCRISTINE (616)
METHOTREXATE (590)
CYTARABINE (573)
ETOPOSIDE (523)
OXALIPLATIN (521)
MELPHALAN (464)
DEXAMETHASONE (371)
Which PEGASPARGASE Alternatives Have Lower Venoocclusive liver disease Risk?
PEGASPARGASE vs PEGASYS
PEGASPARGASE vs PEGCETACOPLAN
PEGASPARGASE vs PEGFILGRASTIM
PEGASPARGASE vs PEGFILGRASTIM-APGF
PEGASPARGASE vs PEGFILGRASTIM-BMEZ