Does PERTUZUMAB Cause Hepatotoxicity? 99 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 99 reports of Hepatotoxicity have been filed in association with PERTUZUMAB (PERJETA). This represents 0.5% of all adverse event reports for PERTUZUMAB.
99
Reports of Hepatotoxicity with PERTUZUMAB
0.5%
of all PERTUZUMAB reports
0
Deaths
29
Hospitalizations
How Dangerous Is Hepatotoxicity From PERTUZUMAB?
Of the 99 reports, 29 (29.3%) required hospitalization, and 6 (6.1%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PERTUZUMAB. However, 99 reports have been filed with the FAERS database.
What Other Side Effects Does PERTUZUMAB Cause?
Diarrhoea (3,343)
Off label use (1,886)
Fatigue (1,672)
Nausea (1,669)
Myelosuppression (1,311)
Disease progression (1,142)
Vomiting (1,096)
Dyspnoea (987)
Neuropathy peripheral (983)
Pyrexia (926)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which PERTUZUMAB Alternatives Have Lower Hepatotoxicity Risk?
PERTUZUMAB vs PERTUZUMAB\TRASTUZUMAB
PERTUZUMAB vs PETROLATUM
PERTUZUMAB vs PEVONEDISTAT
PERTUZUMAB vs PEXIDARTINIB
PERTUZUMAB vs PHENACETIN