Does PONATINIB Cause Hepatotoxicity? 69 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 69 reports of Hepatotoxicity have been filed in association with PONATINIB (Iclusig). This represents 0.7% of all adverse event reports for PONATINIB.
69
Reports of Hepatotoxicity with PONATINIB
0.7%
of all PONATINIB reports
18
Deaths
10
Hospitalizations
How Dangerous Is Hepatotoxicity From PONATINIB?
Of the 69 reports, 18 (26.1%) resulted in death, 10 (14.5%) required hospitalization, and 7 (10.1%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
Yes, Hepatotoxicity is listed as a known adverse reaction in the official FDA drug label for PONATINIB.
What Other Side Effects Does PONATINIB Cause?
Death (1,735)
Off label use (1,071)
Product dose omission issue (817)
Fatigue (687)
Rash (639)
Headache (553)
Pyrexia (542)
Nausea (466)
Hospitalisation (459)
Constipation (435)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which PONATINIB Alternatives Have Lower Hepatotoxicity Risk?
PONATINIB vs PONATINIB\PONATINIB
PONATINIB vs PONESIMOD
PONATINIB vs PORACTANT ALFA
PONATINIB vs PORFIMER
PONATINIB vs POSACONAZOLE