Does PRETOMANID Cause Hepatotoxicity? 22 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 22 reports of Hepatotoxicity have been filed in association with PRETOMANID (Pretomanid). This represents 4.4% of all adverse event reports for PRETOMANID.
22
Reports of Hepatotoxicity with PRETOMANID
4.4%
of all PRETOMANID reports
4
Deaths
7
Hospitalizations
How Dangerous Is Hepatotoxicity From PRETOMANID?
Of the 22 reports, 4 (18.2%) resulted in death, 7 (31.8%) required hospitalization, and 3 (13.6%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
Yes, Hepatotoxicity is listed as a known adverse reaction in the official FDA drug label for PRETOMANID.
What Other Side Effects Does PRETOMANID Cause?
Death (91)
Anaemia (43)
Nausea (32)
Electrocardiogram qt prolonged (30)
Neuropathy peripheral (26)
Acute kidney injury (25)
Off label use (23)
Alanine aminotransferase increased (21)
Aspartate aminotransferase increased (19)
Decreased appetite (14)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which PRETOMANID Alternatives Have Lower Hepatotoxicity Risk?
PRETOMANID vs PREVISCAN
PRETOMANID vs PREZISTA
PRETOMANID vs PRILOCAINE
PRETOMANID vs PRILOSEC
PRETOMANID vs PRILOSEC OTC