Does PYRAZINAMIDE Cause Hepatic cytolysis? 27 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 27 reports of Hepatic cytolysis have been filed in association with PYRAZINAMIDE (Pyrazinamide). This represents 0.5% of all adverse event reports for PYRAZINAMIDE.
27
Reports of Hepatic cytolysis with PYRAZINAMIDE
0.5%
of all PYRAZINAMIDE reports
0
Deaths
23
Hospitalizations
How Dangerous Is Hepatic cytolysis From PYRAZINAMIDE?
Of the 27 reports, 23 (85.2%) required hospitalization, and 3 (11.1%) were considered life-threatening.
Is Hepatic cytolysis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PYRAZINAMIDE. However, 27 reports have been filed with the FAERS database.
What Other Side Effects Does PYRAZINAMIDE Cause?
Drug-induced liver injury (588)
Drug reaction with eosinophilia and systemic symptoms (492)
Paradoxical drug reaction (407)
Vomiting (307)
Pyrexia (301)
Drug ineffective (298)
Off label use (288)
Hepatotoxicity (279)
Drug resistance (269)
Nausea (251)
What Other Drugs Cause Hepatic cytolysis?
ACETAMINOPHEN (1,469)
ATORVASTATIN (681)
PEMBROLIZUMAB (601)
CARBOPLATIN (577)
METHOTREXATE (468)
SULFAMETHOXAZOLE\TRIMETHOPRIM (356)
PACLITAXEL (324)
ENOXAPARIN (307)
AMOXICILLIN (273)
VALACYCLOVIR (261)
Which PYRAZINAMIDE Alternatives Have Lower Hepatic cytolysis Risk?
PYRAZINAMIDE vs PYRIDOSTIGMINE
PYRAZINAMIDE vs PYRIDOXINE
PYRAZINAMIDE vs PYRIDOXINE\THIAMINE
PYRAZINAMIDE vs PYRIMETHAMINE
PYRAZINAMIDE vs PYROTINIB