Does PYRAZINAMIDE Cause Hyperbilirubinaemia? 32 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 32 reports of Hyperbilirubinaemia have been filed in association with PYRAZINAMIDE (Pyrazinamide). This represents 0.6% of all adverse event reports for PYRAZINAMIDE.
32
Reports of Hyperbilirubinaemia with PYRAZINAMIDE
0.6%
of all PYRAZINAMIDE reports
5
Deaths
16
Hospitalizations
How Dangerous Is Hyperbilirubinaemia From PYRAZINAMIDE?
Of the 32 reports, 5 (15.6%) resulted in death, 16 (50.0%) required hospitalization, and 6 (18.8%) were considered life-threatening.
Is Hyperbilirubinaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PYRAZINAMIDE. However, 32 reports have been filed with the FAERS database.
What Other Side Effects Does PYRAZINAMIDE Cause?
Drug-induced liver injury (588)
Drug reaction with eosinophilia and systemic symptoms (492)
Paradoxical drug reaction (407)
Vomiting (307)
Pyrexia (301)
Drug ineffective (298)
Off label use (288)
Hepatotoxicity (279)
Drug resistance (269)
Nausea (251)
What Other Drugs Cause Hyperbilirubinaemia?
METHOTREXATE (603)
RIBAVIRIN (560)
VINCRISTINE (479)
CYTARABINE (397)
PEGASPARGASE (349)
ACETAMINOPHEN (330)
CYCLOPHOSPHAMIDE (330)
DEXAMETHASONE (315)
CAPECITABINE (279)
SOFOSBUVIR (260)
Which PYRAZINAMIDE Alternatives Have Lower Hyperbilirubinaemia Risk?
PYRAZINAMIDE vs PYRIDOSTIGMINE
PYRAZINAMIDE vs PYRIDOXINE
PYRAZINAMIDE vs PYRIDOXINE\THIAMINE
PYRAZINAMIDE vs PYRIMETHAMINE
PYRAZINAMIDE vs PYROTINIB