Does PYRAZINAMIDE Cause Hypertransaminasaemia? 61 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 61 reports of Hypertransaminasaemia have been filed in association with PYRAZINAMIDE (Pyrazinamide). This represents 1.1% of all adverse event reports for PYRAZINAMIDE.
61
Reports of Hypertransaminasaemia with PYRAZINAMIDE
1.1%
of all PYRAZINAMIDE reports
0
Deaths
35
Hospitalizations
How Dangerous Is Hypertransaminasaemia From PYRAZINAMIDE?
Of the 61 reports, 35 (57.4%) required hospitalization, and 1 (1.6%) were considered life-threatening.
Is Hypertransaminasaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PYRAZINAMIDE. However, 61 reports have been filed with the FAERS database.
What Other Side Effects Does PYRAZINAMIDE Cause?
Drug-induced liver injury (588)
Drug reaction with eosinophilia and systemic symptoms (492)
Paradoxical drug reaction (407)
Vomiting (307)
Pyrexia (301)
Drug ineffective (298)
Off label use (288)
Hepatotoxicity (279)
Drug resistance (269)
Nausea (251)
What Other Drugs Cause Hypertransaminasaemia?
METHOTREXATE (436)
ACETAMINOPHEN (326)
PACLITAXEL (318)
CARBOPLATIN (304)
PEMBROLIZUMAB (231)
ATORVASTATIN (207)
CYCLOPHOSPHAMIDE (202)
PREDNISONE (198)
GEMCITABINE (196)
DEXAMETHASONE (169)
Which PYRAZINAMIDE Alternatives Have Lower Hypertransaminasaemia Risk?
PYRAZINAMIDE vs PYRIDOSTIGMINE
PYRAZINAMIDE vs PYRIDOXINE
PYRAZINAMIDE vs PYRIDOXINE\THIAMINE
PYRAZINAMIDE vs PYRIMETHAMINE
PYRAZINAMIDE vs PYROTINIB