Does RIFABUTIN Cause Hepatotoxicity? 43 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 43 reports of Hepatotoxicity have been filed in association with RIFABUTIN (Rifabutin). This represents 2.7% of all adverse event reports for RIFABUTIN.
43
Reports of Hepatotoxicity with RIFABUTIN
2.7%
of all RIFABUTIN reports
1
Deaths
7
Hospitalizations
How Dangerous Is Hepatotoxicity From RIFABUTIN?
Of the 43 reports, 1 (2.3%) resulted in death, 7 (16.3%) required hospitalization, and 1 (2.3%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for RIFABUTIN. However, 43 reports have been filed with the FAERS database.
What Other Side Effects Does RIFABUTIN Cause?
Drug ineffective (171)
Off label use (127)
Drug resistance (123)
Drug interaction (99)
Drug intolerance (97)
Pyrexia (95)
Drug reaction with eosinophilia and systemic symptoms (81)
Nausea (77)
Neutropenia (77)
Mycobacterium avium complex infection (76)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which RIFABUTIN Alternatives Have Lower Hepatotoxicity Risk?
RIFABUTIN vs RIFAMPICIN
RIFABUTIN vs RIFAMPIN
RIFABUTIN vs RIFAMYCIN
RIFABUTIN vs RIFAPENTINE
RIFABUTIN vs RIFAXIMIN