Does RIFAMPIN Cause Hepatotoxicity? 271 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 271 reports of Hepatotoxicity have been filed in association with RIFAMPIN (Rifampin). This represents 2.0% of all adverse event reports for RIFAMPIN.
271
Reports of Hepatotoxicity with RIFAMPIN
2.0%
of all RIFAMPIN reports
78
Deaths
88
Hospitalizations
How Dangerous Is Hepatotoxicity From RIFAMPIN?
Of the 271 reports, 78 (28.8%) resulted in death, 88 (32.5%) required hospitalization, and 16 (5.9%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
Yes, Hepatotoxicity is listed as a known adverse reaction in the official FDA drug label for RIFAMPIN.
What Other Side Effects Does RIFAMPIN Cause?
Drug ineffective (1,238)
Drug reaction with eosinophilia and systemic symptoms (1,049)
Drug interaction (735)
Pyrexia (735)
Acute kidney injury (684)
Drug-induced liver injury (684)
Off label use (640)
Condition aggravated (597)
Nausea (572)
Paradoxical drug reaction (570)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which RIFAMPIN Alternatives Have Lower Hepatotoxicity Risk?
RIFAMPIN vs RIFAMYCIN
RIFAMPIN vs RIFAPENTINE
RIFAMPIN vs RIFAXIMIN
RIFAMPIN vs RILMENIDINE
RIFAMPIN vs RILONACEPT