Does RIFAXIMIN Cause Hepatotoxicity? 11 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 11 reports of Hepatotoxicity have been filed in association with RIFAXIMIN (XIFAXAN). This represents 0.1% of all adverse event reports for RIFAXIMIN.
11
Reports of Hepatotoxicity with RIFAXIMIN
0.1%
of all RIFAXIMIN reports
10
Deaths
11
Hospitalizations
How Dangerous Is Hepatotoxicity From RIFAXIMIN?
Of the 11 reports, 10 (90.9%) resulted in death, 11 (100.0%) required hospitalization, and 10 (90.9%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for RIFAXIMIN. However, 11 reports have been filed with the FAERS database.
What Other Side Effects Does RIFAXIMIN Cause?
Death (3,687)
Hospitalisation (1,605)
Therapy interrupted (875)
Off label use (802)
Diarrhoea (709)
Ammonia increased (676)
Inability to afford medication (672)
Insurance issue (577)
Confusional state (530)
Hepatic cirrhosis (480)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which RIFAXIMIN Alternatives Have Lower Hepatotoxicity Risk?
RIFAXIMIN vs RILMENIDINE
RIFAXIMIN vs RILONACEPT
RIFAXIMIN vs RILPIVIRINE
RIFAXIMIN vs RILUZOLE
RIFAXIMIN vs RIMABOTULINUMTOXINB