Does SIMVASTATIN Cause Hepatotoxicity? 88 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 88 reports of Hepatotoxicity have been filed in association with SIMVASTATIN (Simvastatin). This represents 0.3% of all adverse event reports for SIMVASTATIN.
88
Reports of Hepatotoxicity with SIMVASTATIN
0.3%
of all SIMVASTATIN reports
6
Deaths
40
Hospitalizations
How Dangerous Is Hepatotoxicity From SIMVASTATIN?
Of the 88 reports, 6 (6.8%) resulted in death, 40 (45.5%) required hospitalization, and 6 (6.8%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SIMVASTATIN. However, 88 reports have been filed with the FAERS database.
What Other Side Effects Does SIMVASTATIN Cause?
Myalgia (3,919)
Fatigue (2,066)
Arthralgia (1,775)
Drug interaction (1,744)
Nausea (1,676)
Rhabdomyolysis (1,616)
Dyspnoea (1,542)
Headache (1,470)
Drug hypersensitivity (1,433)
Muscular weakness (1,356)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which SIMVASTATIN Alternatives Have Lower Hepatotoxicity Risk?
SIMVASTATIN vs SINGULAIR
SIMVASTATIN vs SINTILIMAB
SIMVASTATIN vs SIPONIMOD
SIMVASTATIN vs SIPULEUCEL-T
SIMVASTATIN vs SIROLIMUS