Does TACROLIMUS Cause Hepatotoxicity? 141 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 141 reports of Hepatotoxicity have been filed in association with TACROLIMUS (Tacrolimus). This represents 0.2% of all adverse event reports for TACROLIMUS.
141
Reports of Hepatotoxicity with TACROLIMUS
0.2%
of all TACROLIMUS reports
21
Deaths
57
Hospitalizations
How Dangerous Is Hepatotoxicity From TACROLIMUS?
Of the 141 reports, 21 (14.9%) resulted in death, 57 (40.4%) required hospitalization, and 10 (7.1%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
Yes, Hepatotoxicity is listed as a known adverse reaction in the official FDA drug label for TACROLIMUS.
What Other Side Effects Does TACROLIMUS Cause?
Off label use (8,718)
Drug ineffective (6,214)
Product use in unapproved indication (5,057)
Acute kidney injury (4,005)
Transplant rejection (3,526)
Cytomegalovirus infection (3,320)
Covid-19 (3,201)
Drug interaction (2,896)
Diarrhoea (2,854)
Toxicity to various agents (2,845)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which TACROLIMUS Alternatives Have Lower Hepatotoxicity Risk?
TACROLIMUS vs TACROLIMUS\TACROLIMUS ANHYDROUS
TACROLIMUS vs TADALAFIL
TACROLIMUS vs TAFAMIDIS
TACROLIMUS vs TAFAMIDIS MEGLUMINE
TACROLIMUS vs TAFASITAMAB