Does TEMOZOLOMIDE Cause Hepatotoxicity? 46 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 46 reports of Hepatotoxicity have been filed in association with TEMOZOLOMIDE (TEMOZOLOMIDE). This represents 0.3% of all adverse event reports for TEMOZOLOMIDE.
46
Reports of Hepatotoxicity with TEMOZOLOMIDE
0.3%
of all TEMOZOLOMIDE reports
7
Deaths
5
Hospitalizations
How Dangerous Is Hepatotoxicity From TEMOZOLOMIDE?
Of the 46 reports, 7 (15.2%) resulted in death, 5 (10.9%) required hospitalization, and 3 (6.5%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
Yes, Hepatotoxicity is listed as a known adverse reaction in the official FDA drug label for TEMOZOLOMIDE.
What Other Side Effects Does TEMOZOLOMIDE Cause?
Disease progression (1,562)
Death (1,403)
Off label use (1,357)
Product use in unapproved indication (1,353)
Thrombocytopenia (1,300)
Drug ineffective (1,131)
Nausea (1,071)
Neutropenia (809)
Malignant neoplasm progression (779)
Fatigue (766)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which TEMOZOLOMIDE Alternatives Have Lower Hepatotoxicity Risk?
TEMOZOLOMIDE vs TEMSIROLIMUS
TEMOZOLOMIDE vs TENAMFETAMINE
TEMOZOLOMIDE vs TENAPANOR
TEMOZOLOMIDE vs TENECTEPLASE
TEMOZOLOMIDE vs TENELIGLIPTIN