Does THALIDOMIDE Cause Hepatotoxicity? 46 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 46 reports of Hepatotoxicity have been filed in association with THALIDOMIDE (Thalomid). This represents 0.3% of all adverse event reports for THALIDOMIDE.
46
Reports of Hepatotoxicity with THALIDOMIDE
0.3%
of all THALIDOMIDE reports
8
Deaths
11
Hospitalizations
How Dangerous Is Hepatotoxicity From THALIDOMIDE?
Of the 46 reports, 8 (17.4%) resulted in death, 11 (23.9%) required hospitalization, and 6 (13.0%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for THALIDOMIDE. However, 46 reports have been filed with the FAERS database.
What Other Side Effects Does THALIDOMIDE Cause?
Plasma cell myeloma (1,652)
Off label use (1,356)
Death (1,161)
Neuropathy peripheral (1,068)
Drug ineffective (789)
Pneumonia (694)
Fatigue (643)
Constipation (461)
Thrombocytopenia (429)
Neutropenia (420)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which THALIDOMIDE Alternatives Have Lower Hepatotoxicity Risk?
THALIDOMIDE vs THALOMID
THALIDOMIDE vs THEOPHYLLINE
THALIDOMIDE vs THEOPHYLLINE ANHYDROUS
THALIDOMIDE vs THIAMINE
THALIDOMIDE vs THIOCOLCHICOSIDE