Does THIOPENTAL Cause Hepatotoxicity? 10 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 10 reports of Hepatotoxicity have been filed in association with THIOPENTAL. This represents 1.0% of all adverse event reports for THIOPENTAL.
10
Reports of Hepatotoxicity with THIOPENTAL
1.0%
of all THIOPENTAL reports
1
Deaths
6
Hospitalizations
How Dangerous Is Hepatotoxicity From THIOPENTAL?
Of the 10 reports, 1 (10.0%) resulted in death, 6 (60.0%) required hospitalization, and 3 (30.0%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for THIOPENTAL. However, 10 reports have been filed with the FAERS database.
What Other Side Effects Does THIOPENTAL Cause?
Drug ineffective (266)
Off label use (150)
Status epilepticus (93)
Hypotension (82)
Maternal exposure during pregnancy (74)
Foetal exposure during pregnancy (70)
Exposure during pregnancy (64)
Product use in unapproved indication (63)
Diabetes insipidus (55)
Drug hypersensitivity (45)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which THIOPENTAL Alternatives Have Lower Hepatotoxicity Risk?
THIOPENTAL vs THIORIDAZINE
THIOPENTAL vs THIOTEPA
THIOPENTAL vs THIOTHIXENE
THIOPENTAL vs THROMBIN
THIOPENTAL vs THROMBIN HUMAN