Does TOCILIZUMAB Cause Hepatotoxicity? 574 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 574 reports of Hepatotoxicity have been filed in association with TOCILIZUMAB (Tocilizumab-anoh). This represents 0.6% of all adverse event reports for TOCILIZUMAB.
574
Reports of Hepatotoxicity with TOCILIZUMAB
0.6%
of all TOCILIZUMAB reports
26
Deaths
156
Hospitalizations
How Dangerous Is Hepatotoxicity From TOCILIZUMAB?
Of the 574 reports, 26 (4.5%) resulted in death, 156 (27.2%) required hospitalization, and 23 (4.0%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOCILIZUMAB. However, 574 reports have been filed with the FAERS database.
What Other Side Effects Does TOCILIZUMAB Cause?
Drug ineffective (32,342)
Rheumatoid arthritis (20,652)
Pain (18,384)
Off label use (18,256)
Arthralgia (15,536)
Joint swelling (14,831)
Fatigue (13,802)
Rash (12,327)
Drug intolerance (11,952)
Contraindicated product administered (11,547)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which TOCILIZUMAB Alternatives Have Lower Hepatotoxicity Risk?
TOCILIZUMAB vs TOCILIZUMAB-AAZG
TOCILIZUMAB vs TOCOPHEROL
TOCILIZUMAB vs TOFACITINIB
TOCILIZUMAB vs TOFERSEN
TOCILIZUMAB vs TOLNAFTATE