Does TOPIRAMATE Cause Hepatotoxicity? 15 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 15 reports of Hepatotoxicity have been filed in association with TOPIRAMATE (Topiramate). This represents 0.1% of all adverse event reports for TOPIRAMATE.
15
Reports of Hepatotoxicity with TOPIRAMATE
0.1%
of all TOPIRAMATE reports
0
Deaths
10
Hospitalizations
How Dangerous Is Hepatotoxicity From TOPIRAMATE?
Of the 15 reports, 10 (66.7%) required hospitalization.
Is Hepatotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOPIRAMATE. However, 15 reports have been filed with the FAERS database.
What Other Side Effects Does TOPIRAMATE Cause?
Drug ineffective (5,553)
Off label use (4,248)
Product use in unapproved indication (2,173)
Headache (1,997)
Drug intolerance (1,820)
Migraine (1,796)
Nausea (1,691)
Seizure (1,535)
Paraesthesia (1,506)
Dizziness (1,466)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which TOPIRAMATE Alternatives Have Lower Hepatotoxicity Risk?
TOPIRAMATE vs TOPOTECAN
TOPIRAMATE vs TOPOTECAN\TOPOTECAN
TOPIRAMATE vs TOPROL
TOPIRAMATE vs TOREMIFENE
TOPIRAMATE vs TORIPALIMAB