Does TOPOTECAN Cause Large intestine perforation? 8 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 8 reports of Large intestine perforation have been filed in association with TOPOTECAN (HYCAMTIN). This represents 0.2% of all adverse event reports for TOPOTECAN.
8
Reports of Large intestine perforation with TOPOTECAN
0.2%
of all TOPOTECAN reports
0
Deaths
5
Hospitalizations
How Dangerous Is Large intestine perforation From TOPOTECAN?
Of the 8 reports, 5 (62.5%) required hospitalization.
Is Large intestine perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOPOTECAN. However, 8 reports have been filed with the FAERS database.
What Other Side Effects Does TOPOTECAN Cause?
Febrile neutropenia (425)
Off label use (390)
Death (332)
Product use in unapproved indication (323)
Neutropenia (255)
Pyrexia (252)
Anaemia (242)
Malignant neoplasm progression (238)
Drug ineffective (216)
Disease progression (207)
What Other Drugs Cause Large intestine perforation?
ADALIMUMAB (417)
BEVACIZUMAB (406)
DEXAMETHASONE (243)
PACLITAXEL (191)
CARBOPLATIN (174)
PREDNISOLONE (171)
PREDNISONE (165)
METHYLPREDNISOLONE (164)
FLUOROURACIL (162)
PEMBROLIZUMAB (157)
Which TOPOTECAN Alternatives Have Lower Large intestine perforation Risk?
TOPOTECAN vs TOPOTECAN\TOPOTECAN
TOPOTECAN vs TOPROL
TOPOTECAN vs TOREMIFENE
TOPOTECAN vs TORIPALIMAB
TOPOTECAN vs TORSEMIDE