Does TRABECTEDIN Cause Hepatotoxicity? 65 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 65 reports of Hepatotoxicity have been filed in association with TRABECTEDIN (YONDELIS). This represents 3.3% of all adverse event reports for TRABECTEDIN.
65
Reports of Hepatotoxicity with TRABECTEDIN
3.3%
of all TRABECTEDIN reports
23
Deaths
10
Hospitalizations
How Dangerous Is Hepatotoxicity From TRABECTEDIN?
Of the 65 reports, 23 (35.4%) resulted in death, 10 (15.4%) required hospitalization, and 1 (1.5%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
Yes, Hepatotoxicity is listed as a known adverse reaction in the official FDA drug label for TRABECTEDIN.
What Other Side Effects Does TRABECTEDIN Cause?
Neutropenia (207)
Anaemia (189)
Thrombocytopenia (172)
Nausea (160)
Febrile neutropenia (142)
Pancytopenia (124)
Vomiting (121)
Rhabdomyolysis (117)
Off label use (105)
Alanine aminotransferase increased (104)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which TRABECTEDIN Alternatives Have Lower Hepatotoxicity Risk?
TRABECTEDIN vs TRACLEER
TRABECTEDIN vs TRADJENTA
TRABECTEDIN vs TRALOKINUMAB-LDRM
TRABECTEDIN vs TRAMADOL
TRABECTEDIN vs TRAMADOL\TRAMADOL