Does TRASTUZUMAB Cause Hepatotoxicity? 277 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 277 reports of Hepatotoxicity have been filed in association with TRASTUZUMAB (Trazimera). This represents 0.6% of all adverse event reports for TRASTUZUMAB.
277
Reports of Hepatotoxicity with TRASTUZUMAB
0.6%
of all TRASTUZUMAB reports
8
Deaths
46
Hospitalizations
How Dangerous Is Hepatotoxicity From TRASTUZUMAB?
Of the 277 reports, 8 (2.9%) resulted in death, 46 (16.6%) required hospitalization, and 8 (2.9%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TRASTUZUMAB. However, 277 reports have been filed with the FAERS database.
What Other Side Effects Does TRASTUZUMAB Cause?
Diarrhoea (4,996)
Off label use (3,802)
Nausea (3,499)
Fatigue (3,417)
Myelosuppression (2,552)
Disease progression (2,449)
Death (2,378)
Vomiting (2,244)
Dyspnoea (2,010)
Pyrexia (1,886)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which TRASTUZUMAB Alternatives Have Lower Hepatotoxicity Risk?
TRASTUZUMAB vs TRASTUZUMAB-ANNS
TRASTUZUMAB vs TRASTUZUMAB DERUXTECAN
TRASTUZUMAB vs TRASTUZUMAB-DKST
TRASTUZUMAB vs TRASTUZUMAB-DTTB
TRASTUZUMAB vs TRASTUZUMAB EMTANSINE