Does TREOSULFAN Cause Hepatotoxicity? 17 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 17 reports of Hepatotoxicity have been filed in association with TREOSULFAN (GRAFAPEX). This represents 1.0% of all adverse event reports for TREOSULFAN.
17
Reports of Hepatotoxicity with TREOSULFAN
1.0%
of all TREOSULFAN reports
1
Deaths
6
Hospitalizations
How Dangerous Is Hepatotoxicity From TREOSULFAN?
Of the 17 reports, 1 (5.9%) resulted in death, 6 (35.3%) required hospitalization, and 1 (5.9%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
Yes, Hepatotoxicity is listed as a known adverse reaction in the official FDA drug label for TREOSULFAN.
What Other Side Effects Does TREOSULFAN Cause?
Off label use (418)
Cytomegalovirus infection (211)
Mucosal inflammation (199)
Cytomegalovirus infection reactivation (190)
Adenovirus infection (168)
Product use in unapproved indication (161)
Acute graft versus host disease in skin (145)
Drug ineffective (117)
Graft versus host disease in skin (109)
Human herpesvirus 6 infection (104)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which TREOSULFAN Alternatives Have Lower Hepatotoxicity Risk?
TREOSULFAN vs TREPROSTINIL
TREOSULFAN vs TREPROSTINIL DIOLAMINE
TREOSULFAN vs TRETINOIN
TREOSULFAN vs TRIAMCINOLONE
TREOSULFAN vs TRIAMCINOLONE ACETONIDE