Does TRETINOIN Cause Hepatotoxicity? 27 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 27 reports of Hepatotoxicity have been filed in association with TRETINOIN (Tretinoin). This represents 0.7% of all adverse event reports for TRETINOIN.
27
Reports of Hepatotoxicity with TRETINOIN
0.7%
of all TRETINOIN reports
13
Deaths
2
Hospitalizations
How Dangerous Is Hepatotoxicity From TRETINOIN?
Of the 27 reports, 13 (48.1%) resulted in death, 2 (7.4%) required hospitalization, and 5 (18.5%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
Yes, Hepatotoxicity is listed as a known adverse reaction in the official FDA drug label for TRETINOIN.
What Other Side Effects Does TRETINOIN Cause?
Off label use (665)
Drug ineffective (537)
Product use in unapproved indication (466)
Vomiting (286)
Paraesthesia (284)
Pain (270)
Drug intolerance (263)
Maternal exposure during pregnancy (261)
Taste disorder (258)
Differentiation syndrome (251)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which TRETINOIN Alternatives Have Lower Hepatotoxicity Risk?
TRETINOIN vs TRIAMCINOLONE
TRETINOIN vs TRIAMCINOLONE ACETONIDE
TRETINOIN vs TRIAMCINOLONE HEXACETONIDE
TRETINOIN vs TRIAMTERENE
TRETINOIN vs TRIATEC