Does TRIMETHOPRIM Cause Hepatotoxicity? 36 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 36 reports of Hepatotoxicity have been filed in association with TRIMETHOPRIM (Trimethoprim). This represents 1.1% of all adverse event reports for TRIMETHOPRIM.
36
Reports of Hepatotoxicity with TRIMETHOPRIM
1.1%
of all TRIMETHOPRIM reports
22
Deaths
33
Hospitalizations
How Dangerous Is Hepatotoxicity From TRIMETHOPRIM?
Of the 36 reports, 22 (61.1%) resulted in death, 33 (91.7%) required hospitalization, and 18 (50.0%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TRIMETHOPRIM. However, 36 reports have been filed with the FAERS database.
What Other Side Effects Does TRIMETHOPRIM Cause?
Headache (409)
Nausea (383)
Off label use (376)
Drug ineffective (368)
Malaise (346)
Swelling face (267)
Hypersensitivity (260)
Acute kidney injury (249)
Rash (235)
Drug intolerance (231)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which TRIMETHOPRIM Alternatives Have Lower Hepatotoxicity Risk?
TRIMETHOPRIM vs TRIMIPRAMINE
TRIMETHOPRIM vs TRIPROLIDINE
TRIMETHOPRIM vs TRIPTORELIN
TRIMETHOPRIM vs TRISODIUM
TRIMETHOPRIM vs TROFINETIDE