Does VEMURAFENIB Cause Hepatotoxicity? 61 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 61 reports of Hepatotoxicity have been filed in association with VEMURAFENIB (ZELBORAF). This represents 0.7% of all adverse event reports for VEMURAFENIB.
61
Reports of Hepatotoxicity with VEMURAFENIB
0.7%
of all VEMURAFENIB reports
5
Deaths
13
Hospitalizations
How Dangerous Is Hepatotoxicity From VEMURAFENIB?
Of the 61 reports, 5 (8.2%) resulted in death, 13 (21.3%) required hospitalization, and 4 (6.6%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
Yes, Hepatotoxicity is listed as a known adverse reaction in the official FDA drug label for VEMURAFENIB.
What Other Side Effects Does VEMURAFENIB Cause?
Rash (1,202)
Arthralgia (783)
Off label use (782)
Fatigue (773)
Diarrhoea (655)
Nausea (601)
Pyrexia (569)
Death (505)
Alopecia (445)
Decreased appetite (383)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which VEMURAFENIB Alternatives Have Lower Hepatotoxicity Risk?
VEMURAFENIB vs VENETOCLAX
VEMURAFENIB vs VENLAFAXINE
VEMURAFENIB vs VENTAVIS
VEMURAFENIB vs VENTOLIN
VEMURAFENIB vs VENTOLIN HFA