Does VINCRISTINE Cause Hepatotoxicity? 474 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 474 reports of Hepatotoxicity have been filed in association with VINCRISTINE (VinCRIStine Sulfate). This represents 0.7% of all adverse event reports for VINCRISTINE.
474
Reports of Hepatotoxicity with VINCRISTINE
0.7%
of all VINCRISTINE reports
69
Deaths
132
Hospitalizations
How Dangerous Is Hepatotoxicity From VINCRISTINE?
Of the 474 reports, 69 (14.6%) resulted in death, 132 (27.8%) required hospitalization, and 67 (14.1%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for VINCRISTINE. However, 474 reports have been filed with the FAERS database.
What Other Side Effects Does VINCRISTINE Cause?
Febrile neutropenia (8,676)
Off label use (6,562)
Disease progression (5,252)
Neutropenia (4,982)
Drug ineffective (4,084)
Pyrexia (3,460)
Product use in unapproved indication (3,073)
Thrombocytopenia (2,940)
Sepsis (2,791)
Anaemia (2,603)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which VINCRISTINE Alternatives Have Lower Hepatotoxicity Risk?
VINCRISTINE vs VINDESINE
VINCRISTINE vs VINORELBINE
VINCRISTINE vs VINORELBINE\VINORELBINE
VINCRISTINE vs VIREAD
VINCRISTINE vs VISIPAQUE