Dopamine dysregulation syndrome: Which Medications Cause It? (314 Reports Across 21 Drugs)
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Dopamine dysregulation syndrome has been reported as an adverse event with 21 different drugs in the FDA's FAERS database, with 314 total reports. 6 of these reports resulted in death.The drugs most commonly associated with Dopamine dysregulation syndrome are CARBIDOPA\LEVODOPA, ROPINIROLE, and PRAMIPEXOLE.
314
Total Reports
21
Drugs Involved
6
Deaths
157
Hospitalizations
59.5 yrs
Average Patient Age
29.4% / 70.6%
Female / Male
Which Drugs Cause Dopamine dysregulation syndrome Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| CARBIDOPA\LEVODOPA | 167 | 0.3% | 2 | 94 | 8 |
| ROPINIROLE | 64 | 1.5% | 3 | 39 | 5 |
| PRAMIPEXOLE | 54 | 0.9% | 0 | 13 | 0 |
| LEVODOPA | 39 | 0.6% | 3 | 13 | 4 |
| CARBIDOPA\ENTACAPONE\LEVODOPA | 24 | 1.0% | 0 | 18 | 0 |
| AMANTADINE | 21 | 0.4% | 0 | 18 | 0 |
| BENSERAZIDE\LEVODOPA | 21 | 1.0% | 0 | 17 | 0 |
| ENTACAPONE | 21 | 1.5% | 0 | 10 | 0 |
| ARIPIPRAZOLE | 20 | 0.0% | 0 | 12 | 0 |
| RASAGILINE | 20 | 0.7% | 0 | 13 | 1 |
| RISPERIDONE | 19 | 0.0% | 0 | 12 | 0 |
| ROTIGOTINE | 16 | 0.2% | 0 | 9 | 4 |
| APOMORPHINE | 13 | 0.2% | 0 | 8 | 0 |
| SELEGILINE | 13 | 1.4% | 0 | 12 | 1 |
| PERGOLIDE | 10 | 14.9% | 0 | 9 | 0 |
| L-DOPA | 8 | 42.1% | 0 | 0 | 0 |
| QUETIAPINE | 8 | 0.0% | 0 | 6 | 1 |
| CARBIDOPA/LEVODOPA | 6 | 27.3% | 0 | 2 | 0 |
| PRAMIPEXOLE\PRAMIPEXOLE | 6 | 1.8% | 0 | 5 | 0 |
| SERTRALINE | 6 | 0.0% | 0 | 2 | 0 |