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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Foot amputation: Which Medications Cause It? (1,141 Reports Across 56 Drugs)

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Foot amputation has been reported as an adverse event with 56 different drugs in the FDA's FAERS database, with 1,141 total reports. 43 of these reports resulted in death.The drugs most commonly associated with Foot amputation are CANAGLIFLOZIN, CANAGLIFLOZIN\METFORMIN, and INSULIN GLARGINE.

1,141
Total Reports
56
Drugs Involved
43
Deaths
840
Hospitalizations
57.9 yrs
Average Patient Age
27.1% / 72.9%
Female / Male

Which Drugs Cause Foot amputation Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
CANAGLIFLOZIN 580 2.4% 10 489 5
CANAGLIFLOZIN\METFORMIN 59 3.8% 0 55 0
INSULIN GLARGINE 45 0.1% 1 22 0
EMPAGLIFLOZIN 39 0.1% 2 28 6
METFORMIN 37 0.0% 0 33 0
BECAPLERMIN 24 1.2% 0 17 0
INSULIN ASPART 24 0.1% 0 16 1
ADALIMUMAB 19 0.0% 1 9 0
DAPAGLIFLOZIN 18 0.1% 4 13 0
OXYCODONE 14 0.0% 4 6 1
CIPROFLOXACIN 13 0.0% 0 8 0
DAPAGLIFLOZIN PROPANEDIOL 12 0.1% 0 6 0
SEMAGLUTIDE 12 0.0% 0 7 0
ETANERCEPT 10 0.0% 0 1 0
INSULIN DEGLUDEC 10 0.1% 0 7 1
AMBRISENTAN 9 0.0% 1 9 0
DARBEPOETIN ALFA 9 0.0% 6 8 0
LAMOTRIGINE 9 0.0% 0 9 8
MORPHINE 9 0.0% 3 4 1
PATIROMER 9 0.1% 2 8 0

View all 56 drugs →

Top 3 Drugs Associated With Foot amputation

580 reports
45 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)