Gastrooesophageal reflux disease: Which Medications Cause It? (54,985 Reports Across 1,383 Drugs)
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Gastrooesophageal reflux disease has been reported as an adverse event with 1,383 different drugs in the FDA's FAERS database, with 54,985 total reports. 2,388 of these reports resulted in death.The drugs most commonly associated with Gastrooesophageal reflux disease are ESOMEPRAZOLE, OMEPRAZOLE, and PANTOPRAZOLE.
54,985
Total Reports
1,383
Drugs Involved
2,388
Deaths
15,440
Hospitalizations
57.2 yrs
Average Patient Age
69.3% / 30.7%
Female / Male
Which Drugs Cause Gastrooesophageal reflux disease Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| ESOMEPRAZOLE | 4,746 | 6.3% | 119 | 826 | 23 |
| OMEPRAZOLE | 3,929 | 4.5% | 118 | 628 | 37 |
| PANTOPRAZOLE | 3,456 | 4.4% | 328 | 967 | 214 |
| PREDNISONE | 2,797 | 1.8% | 626 | 1,727 | 715 |
| LANSOPRAZOLE | 2,482 | 4.1% | 122 | 352 | 29 |
| ADALIMUMAB | 2,450 | 0.5% | 725 | 1,210 | 697 |
| ALENDRONATE | 2,046 | 7.3% | 705 | 1,729 | 659 |
| ALBUTEROL | 2,019 | 2.1% | 34 | 1,024 | 120 |
| OLMESARTAN MEDOXOMIL | 1,819 | 15.2% | 19 | 1,304 | 41 |
| METHOTREXATE | 1,757 | 0.7% | 778 | 922 | 722 |
| RANITIDINE | 1,508 | 0.4% | 476 | 913 | 440 |
| RITUXIMAB | 1,416 | 0.8% | 839 | 887 | 725 |
| BUDESONIDE\FORMOTEROL | 1,388 | 3.8% | 7 | 694 | 40 |
| TOFACITINIB | 1,342 | 0.9% | 608 | 608 | 573 |
| MONTELUKAST | 1,330 | 4.9% | 4 | 748 | 62 |
| HYDROCHLOROTHIAZIDE\OLMESARTAN MEDOXOMIL | 1,317 | 22.8% | 12 | 944 | 0 |
| ETANERCEPT | 1,292 | 0.4% | 529 | 650 | 539 |
| APREMILAST | 1,290 | 0.9% | 598 | 539 | 555 |
| NAPROXEN | 1,244 | 2.4% | 622 | 747 | 569 |
| MEPOLIZUMAB | 1,212 | 2.8% | 579 | 821 | 509 |