Muscle rigidity: Which Medications Cause It? (8,078 Reports Across 401 Drugs)
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Muscle rigidity has been reported as an adverse event with 401 different drugs in the FDA's FAERS database, with 8,078 total reports. 491 of these reports resulted in death.The drugs most commonly associated with Muscle rigidity are CARBIDOPA\LEVODOPA, QUETIAPINE, and OLANZAPINE.
8,078
Total Reports
401
Drugs Involved
491
Deaths
3,851
Hospitalizations
54.0 yrs
Average Patient Age
52.0% / 48.0%
Female / Male
Which Drugs Cause Muscle rigidity Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| CARBIDOPA\LEVODOPA | 1,671 | 2.9% | 128 | 862 | 51 |
| QUETIAPINE | 645 | 0.9% | 30 | 408 | 137 |
| OLANZAPINE | 524 | 1.0% | 32 | 323 | 75 |
| RISPERIDONE | 521 | 0.7% | 21 | 297 | 39 |
| ARIPIPRAZOLE | 393 | 0.6% | 30 | 190 | 41 |
| HALOPERIDOL | 323 | 2.0% | 41 | 203 | 53 |
| CLOZAPINE | 256 | 0.3% | 10 | 141 | 19 |
| SERTRALINE | 238 | 0.4% | 32 | 148 | 17 |
| BACLOFEN | 187 | 0.7% | 4 | 96 | 17 |
| MIRTAZAPINE | 176 | 0.6% | 9 | 115 | 58 |
| LITHIUM | 174 | 1.2% | 7 | 124 | 32 |
| PALIPERIDONE | 174 | 0.4% | 4 | 76 | 10 |
| ESCITALOPRAM OXALATE | 172 | 0.6% | 28 | 101 | 48 |
| VENLAFAXINE | 172 | 0.4% | 7 | 111 | 49 |
| FENTANYL | 167 | 0.2% | 20 | 83 | 55 |
| LORAZEPAM | 162 | 0.5% | 9 | 125 | 49 |
| LAMOTRIGINE | 158 | 0.3% | 9 | 117 | 32 |
| DIAZEPAM | 139 | 0.4% | 7 | 93 | 59 |
| CITALOPRAM HYDROBROMIDE | 130 | 0.5% | 1 | 81 | 12 |
| FLUOXETINE | 130 | 0.4% | 1 | 68 | 29 |