Rebound acid hypersecretion: Which Medications Cause It? (3,025 Reports Across 10 Drugs)
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Rebound acid hypersecretion has been reported as an adverse event with 10 different drugs in the FDA's FAERS database, with 3,025 total reports. 445 of these reports resulted in death.The drugs most commonly associated with Rebound acid hypersecretion are ESOMEPRAZOLE, OMEPRAZOLE, and LANSOPRAZOLE.
3,025
Total Reports
10
Drugs Involved
445
Deaths
352
Hospitalizations
57.6 yrs
Average Patient Age
58.2% / 41.8%
Female / Male
Which Drugs Cause Rebound acid hypersecretion Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| ESOMEPRAZOLE | 2,501 | 3.3% | 373 | 291 | 3 |
| OMEPRAZOLE | 2,350 | 2.7% | 350 | 291 | 16 |
| LANSOPRAZOLE | 1,713 | 2.8% | 231 | 187 | 2 |
| PANTOPRAZOLE | 1,581 | 2.0% | 226 | 195 | 15 |
| DEXLANSOPRAZOLE | 1,160 | 4.8% | 139 | 108 | 0 |
| OMEPRAZOLE\SODIUM BICARBONATE | 95 | 4.9% | 12 | 14 | 0 |
| RABEPRAZOLE | 64 | 0.6% | 10 | 11 | 0 |
| RANITIDINE | 29 | 0.0% | 1 | 3 | 0 |
| FAMOTIDINE | 12 | 0.1% | 0 | 2 | 0 |
| ESOMEPRAZOLE\NAPROXEN | 9 | 0.2% | 4 | 0 | 0 |