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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Restlessness: Which Medications Cause It? (24,500 Reports Across 883 Drugs)

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Restlessness has been reported as an adverse event with 883 different drugs in the FDA's FAERS database, with 24,500 total reports. 1,140 of these reports resulted in death.The drugs most commonly associated with Restlessness are ARIPIPRAZOLE, QUETIAPINE, and CARBIDOPA\LEVODOPA.

24,500
Total Reports
883
Drugs Involved
1,140
Deaths
7,318
Hospitalizations
50.0 yrs
Average Patient Age
55.6% / 44.4%
Female / Male

Which Drugs Cause Restlessness Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
ARIPIPRAZOLE 1,219 1.8% 25 406 59
QUETIAPINE 969 1.3% 24 446 99
CARBIDOPA\LEVODOPA 922 1.6% 77 536 19
OLANZAPINE 786 1.5% 20 367 51
SERTRALINE 634 1.1% 30 221 79
PREGABALIN 618 0.6% 17 215 36
SODIUM 601 2.6% 3 20 3
RISPERIDONE 582 0.7% 32 260 37
LURASIDONE 556 3.2% 3 51 8
VENLAFAXINE 488 1.0% 6 202 56
VALBENAZINE 426 1.8% 1 23 1
DULOXETINE 410 0.8% 6 92 22
DIAZEPAM 386 1.0% 46 201 95
LORAZEPAM 386 1.2% 24 186 67
CLONAZEPAM 370 0.9% 19 162 56
MIRTAZAPINE 369 1.3% 26 133 58
ESCITALOPRAM OXALATE 365 1.2% 25 153 49
CITALOPRAM HYDROBROMIDE 358 1.3% 2 145 42
SODIUM OXYBATE 350 0.6% 0 18 0
PALIPERIDONE 331 0.8% 4 95 11

View all 883 drugs →

Top 3 Drugs Associated With Restlessness

1,219 reports
969 reports
922 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)