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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Vulvovaginal discomfort: Which Medications Cause It? (3,145 Reports Across 93 Drugs)

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Vulvovaginal discomfort has been reported as an adverse event with 93 different drugs in the FDA's FAERS database, with 3,145 total reports. 10 of these reports resulted in death.The drugs most commonly associated with Vulvovaginal discomfort are ESTRADIOL, MICONAZOLE, and ESTROGENS, CONJUGATED.

3,145
Total Reports
93
Drugs Involved
10
Deaths
200
Hospitalizations
52.3 yrs
Average Patient Age
99.7% / 0.3%
Female / Male

Which Drugs Cause Vulvovaginal discomfort Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
ESTRADIOL 757 2.4% 0 15 0
MICONAZOLE 487 8.5% 0 2 0
ESTROGENS, CONJUGATED 165 1.8% 0 7 1
ETHINYL ESTRADIOL\ETONOGESTREL 157 1.4% 0 10 2
LEVONORGESTREL 148 0.1% 0 7 3
TIOCONAZOLE 143 10.0% 0 0 0
COPPER 123 0.3% 0 1 0
EMPAGLIFLOZIN 53 0.1% 0 2 1
PRASTERONE 40 2.6% 0 0 0
ADALIMUMAB 33 0.0% 0 6 1
HYDROXYPROGESTERONE CAPROATE 31 0.1% 0 8 0
OSPEMIFENE 28 1.4% 0 0 0
TOCILIZUMAB 25 0.0% 0 11 0
DAPAGLIFLOZIN PROPANEDIOL 22 0.1% 0 0 0
ETONOGESTREL 21 0.1% 0 1 0
METRONIDAZOLE 21 0.1% 0 0 0
RITUXIMAB 21 0.0% 0 8 0
DAPAGLIFLOZIN 20 0.1% 0 3 0
CANAGLIFLOZIN 18 0.1% 0 1 0
CLINDAMYCIN 17 0.1% 0 8 0

View all 93 drugs →

Top 3 Drugs Associated With Vulvovaginal discomfort

757 reports
487 reports
165 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)