Aldosterone Antagonist [EPC]: Side Effects & Safety Data for 2 Drugs
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Aldosterone Antagonist [EPC] includes 2 drugs with a combined 24,788 adverse event reports in the FDA FAERS database. Compare their safety profiles, side effects, and outcomes below.
2
Drugs in Class
24,788
Combined Reports
All Aldosterone Antagonist [EPC] Drugs Ranked by Reports
| Drug | Brand Name | Reports | Deaths | Hosp. | Death Rate |
|---|---|---|---|---|---|
| SPIRONOLACTONE | spironolactone | 21,052 | 1,809 | 11,611 | 8.6% |
| EPLERENONE | Inspra | 3,736 | 224 | 2,148 | 6.0% |
Common Side Effects in Aldosterone Antagonist [EPC] Drugs
| Side Effect | Reports | Deaths |
|---|---|---|
| Acute kidney injury | 3,843 | 290 |
| Hyperkalaemia | 2,766 | 168 |
| Hypotension | 1,981 | 155 |
| Dyspnoea | 1,863 | 87 |
| Drug ineffective | 1,623 | 75 |
| Hyponatraemia | 1,291 | 73 |
| Dizziness | 1,239 | 44 |
| Fatigue | 1,192 | 31 |
| Cardiac failure | 1,119 | 184 |
| Off label use | 1,087 | 60 |