Estrogen Agonist/Antagonist [EPC]: Side Effects & Safety Data for 5 Drugs
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Estrogen Agonist/Antagonist [EPC] includes 5 drugs with a combined 16,268 adverse event reports in the FDA FAERS database. Compare their safety profiles, side effects, and outcomes below.
5
Drugs in Class
16,268
Combined Reports
All Estrogen Agonist/Antagonist [EPC] Drugs Ranked by Reports
| Drug | Brand Name | Reports | Deaths | Hosp. | Death Rate |
|---|---|---|---|---|---|
| TAMOXIFEN | Tamoxifen Citrate | 9,105 | 811 | 1,754 | 8.9% |
| RALOXIFENE | Raloxifene Hydrochloride | 4,185 | 34 | 346 | 0.8% |
| OSPEMIFENE | Osphena | 2,047 | 2 | 60 | 0.1% |
| CLOMIPHENE | Clomiphene Citrate | 686 | 27 | 195 | 3.9% |
| TOREMIFENE | Fareston | 245 | 16 | 92 | 6.5% |
Common Side Effects in Estrogen Agonist/Antagonist [EPC] Drugs
| Side Effect | Reports | Deaths |
|---|---|---|
| Malignant neoplasm progression | 1,504 | 90 |
| Off label use | 927 | 61 |
| Fatigue | 905 | 67 |
| Metastases to bone | 905 | 51 |
| Hot flush | 863 | 1 |
| Nausea | 851 | 68 |
| Drug ineffective | 791 | 68 |
| Arthralgia | 738 | 7 |
| Pain | 714 | 55 |
| Headache | 678 | 51 |