Estrogen Agonist/Antagonist [EPC] — Common Side Effects
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| Side Effect | Total Reports | Drugs | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| Malignant neoplasm progression | 1,504 | 2 | 90 | 105 | 19 |
| Off label use | 927 | 4 | 61 | 130 | 18 |
| Metastases to bone | 905 | 3 | 51 | 56 | 18 |
| Fatigue | 905 | 5 | 67 | 152 | 21 |
| Hot flush | 863 | 4 | 1 | 41 | 5 |
| Nausea | 851 | 5 | 68 | 254 | 17 |
| Drug ineffective | 791 | 5 | 68 | 103 | 32 |
| Arthralgia | 738 | 4 | 7 | 70 | 18 |
| Pain | 714 | 5 | 55 | 122 | 20 |
| Headache | 678 | 4 | 51 | 122 | 21 |
| Muscle spasms | 650 | 4 | 7 | 47 | 10 |
| Diarrhoea | 637 | 4 | 78 | 197 | 6 |
| Breast cancer | 626 | 2 | 23 | 69 | 4 |
| Pain in extremity | 595 | 4 | 5 | 61 | 16 |
| Metastases to liver | 595 | 1 | 44 | 42 | 13 |
| Disease progression | 576 | 2 | 128 | 75 | 10 |
| Breast cancer metastatic | 520 | 2 | 26 | 47 | 4 |
| Dyspnoea | 458 | 5 | 56 | 167 | 20 |
| Asthenia | 450 | 5 | 66 | 130 | 29 |
| Vomiting | 436 | 4 | 76 | 180 | 9 |
| Body height decreased | 405 | 2 | 0 | 4 | 0 |
| Dizziness | 402 | 4 | 6 | 63 | 11 |
| Insomnia | 389 | 4 | 23 | 66 | 4 |
| Death | 379 | 2 | 379 | 61 | 9 |
| Neoplasm progression | 374 | 1 | 26 | 52 | 7 |
| Malaise | 371 | 4 | 50 | 121 | 22 |
| Metastases to lung | 347 | 2 | 23 | 27 | 20 |
| Back pain | 337 | 3 | 77 | 109 | 3 |
| Alopecia | 337 | 4 | 12 | 21 | 4 |
| Weight increased | 331 | 4 | 0 | 56 | 0 |