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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Folate Analog Metabolic Inhibitor [EPC]: Side Effects & Safety Data for 4 Drugs

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Folate Analog Metabolic Inhibitor [EPC] includes 4 drugs with a combined 278,064 adverse event reports in the FDA FAERS database. Compare their safety profiles, side effects, and outcomes below.

4
Drugs in Class
278,064
Combined Reports

All Folate Analog Metabolic Inhibitor [EPC] Drugs Ranked by Reports

Drug Brand Name Reports Deaths Hosp. Death Rate
METHOTREXATE Methotrexate 253,987 21,265 68,793 8.4%
PEMETREXED Pemetrexed 23,543 3,876 10,697 16.5%
PRALATREXATE Pralatrexate 466 120 160 25.8%
PEMETREXED HEMIPENTAHYDRATE PEMRYDI RTU 68 9 35 13.2%

Common Side Effects in Folate Analog Metabolic Inhibitor [EPC] Drugs

Side EffectReportsDeaths
Drug ineffective 71,012 2,840
Rheumatoid arthritis 29,300 2,121
Off label use 25,719 3,731
Pain 23,993 2,021
Drug intolerance 22,684 1,508
Arthralgia 21,991 1,784
Fatigue 20,763 2,096
Nausea 19,923 1,702
Joint swelling 17,703 1,964
Drug hypersensitivity 16,743 1,417
View detailed side effects for this class → Compare drugs in this class →