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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Folic Acid Metabolism Inhibitors [MoA]: Side Effects & Safety Data for 3 Drugs

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Folic Acid Metabolism Inhibitors [MoA] includes 3 drugs with a combined 277,598 adverse event reports in the FDA FAERS database. Compare their safety profiles, side effects, and outcomes below.

3
Drugs in Class
277,598
Combined Reports

All Folic Acid Metabolism Inhibitors [MoA] Drugs Ranked by Reports

Drug Brand Name Reports Deaths Hosp. Death Rate
METHOTREXATE Methotrexate 253,987 21,265 68,793 8.4%
PEMETREXED Pemetrexed 23,543 3,876 10,697 16.5%
PEMETREXED HEMIPENTAHYDRATE PEMRYDI RTU 68 9 35 13.2%

Common Side Effects in Folic Acid Metabolism Inhibitors [MoA] Drugs

Side EffectReportsDeaths
Drug ineffective 70,980 2,831
Rheumatoid arthritis 29,300 2,121
Off label use 25,689 3,725
Pain 23,984 2,020
Drug intolerance 22,674 1,504
Arthralgia 21,991 1,784
Fatigue 20,752 2,096
Nausea 19,910 1,701
Joint swelling 17,703 1,964
Drug hypersensitivity 16,743 1,417
View detailed side effects for this class → Compare drugs in this class →