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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Folic Acid Metabolism Inhibitors [MoA] — Common Side Effects

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Side Effect Total Reports Drugs Deaths Hosp. Life-Threat.
Drug ineffective 70,980 2 2,831 9,958 2,967
Rheumatoid arthritis 29,300 2 2,121 6,696 2,662
Off label use 25,689 3 3,725 8,533 3,823
Pain 23,984 2 2,020 6,026 2,774
Drug intolerance 22,674 2 1,504 4,309 2,012
Arthralgia 21,991 2 1,784 5,818 2,156
Fatigue 20,752 2 2,096 5,763 2,640
Nausea 19,910 2 1,701 6,445 2,149
Joint swelling 17,703 2 1,964 4,459 2,564
Drug hypersensitivity 16,743 2 1,417 4,005 1,814
Rash 16,270 2 2,223 5,223 2,582
Condition aggravated 15,213 2 1,995 4,986 2,281
Treatment failure 14,754 2 1,199 2,616 1,455
Alopecia 14,475 2 1,675 3,252 2,181
Diarrhoea 13,727 3 2,241 5,613 2,362
Abdominal discomfort 13,267 2 1,789 3,613 2,199
Contraindicated product administered 13,121 1 1,305 3,339 1,744
Headache 11,943 2 1,716 4,481 2,006
Vomiting 11,862 2 2,118 5,644 2,471
Synovitis 11,451 1 1,943 3,783 2,328
Arthropathy 10,989 2 1,650 3,891 2,214
Pneumonia 10,960 2 2,751 5,582 1,979
Pyrexia 10,931 2 1,881 6,412 2,178
Swelling 10,723 2 1,908 3,130 2,305
Peripheral swelling 10,702 2 1,539 3,690 1,702
Infection 10,610 2 1,986 3,886 1,592
Malaise 10,236 2 1,699 3,986 1,933
Pain in extremity 10,024 2 1,217 3,061 1,257
Hypersensitivity 9,920 2 1,627 3,511 2,014
Musculoskeletal stiffness 9,918 2 1,486 3,013 1,823
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